Our group is interested in the analysis of the structural basis of the Human brain in order to understand its
function and dysfunction.
We use several approaches:
(1) comparative anatomy;
(2) developmental anatomy;
(3) analysis of brains affected by various neurodegenerative diseases;
(4) expression and regulation of glycoconjugates in the brain during development,
ageing and disease.
Comparative studies include the organization of sensory (auditory, visual, olfactory, general sensory and magnetoreceptive neuronal) pathways and the identification of neurotransmitters in the brain that allow the regulation of a variety of basic functions, such as movement, feeding and circadian rhythmicity.
Developmental anatomy encompasses various projects to characterize structural and molecular processes which are involved in segmentation, migration, homing and differentiation of brain areas. These projects are also intended to create an image database and 3D applications for research and education.
Analysis of "normal" brains and brains affected by various neurodegenerative diseases.
We are providing datasets of adult human anatomic topography and topometry which will serve as reference datasets for many areas of student education and research. Part of this project is the development of the Atlas of the Human Brain and its electronic applications including modelling tools and databasing. We expect that such applications will be available as open resources and be of interest to those working in the areas of education in both basic and clinical sciences. Brains affected by various neurodegenerative diseases are studied using immunohistochemical and molecular technologies.
Expression and regulation of glycoconjugates in the brain during development,
ageing and disease Histochemistry – CD15
Atlas of the Human Brain
Prof. Jürgen K. Mai
Institut für Anatomie I